Article
31P nuclear magnetic resonance studies of growth inhibition and dexamethasone resistance in human leukemic cells.
Cancer letters - 30 May 1990
Post J F, Baum E
Abstract excerpt
31P Nuclear magnetic resonance spectra of perchloric acid extracts from wild-type human leukemic CEM-C7 cells and the dexamethasone-resistant CEM-C1 mutant reveal significant differences in concentrations of phospholipid precursors and ATP+, which indicate metabolic differences between these two...
Topics
- Adenosine Triphosphate
- Animals
- Cattle
- Cell Division
- Dexamethasone
- Drug Resistance
- Humans
- Interphase
- Leukemia
- Magnetic Resonance Spectroscopy
- Mutation
- Organophosphates
- Phosphorus
- Tumor Cells, Cultured
