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Article

TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.

Molecular and cellular biology - 14 May 2020

Fan Xiaochen, Waardenberg Ashley J, Demuth Madeleine, Osteil Pierre, Sun Jane Q J, Loebel David A F, Graham Mark, Tam Patrick P L, Fossat Nicolas

Abstract excerpt

The extensive array of basic helix-loop-helix (bHLH) transcription factors and their combinations as dimers underpin the diversity of molecular function required for cell type specification during embryogenesis. The bHLH factor TWIST1 plays pleiotropic roles during development. However, which combinations of TWIST1 dimers are involved and what impact each dimer imposes on the gene regulation network controlled by...

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Identifiers

PMID: 32179550
DOI: 10.1128/MCB.00663-19
PMCID: PMC7225560

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TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.PMID 32179550Read ↗

TWIST1 homodimers and heterodimers orchestrate lineage-specific differentiationSemantic proximity Read ↗

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