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Article

Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.

Pediatric blood & cancer - 1 Aug 2013

Visscher H, Ross C J D, Rassekh S R, Sandor G S S, Caron H N, van Dalen E C, Kremer L C, van der Pal H J, Rogers P C, Rieder M J, Carleton B C, Hayden M R

Abstract excerpt

BACKGROUND: The use of anthracyclines as effective antineoplastic drugs is limited by the occurrence of cardiotoxicity. Multiple genetic variants predictive of anthracycline-induced cardiotoxicity (ACT) in children were recently identified. The current study was aimed to assess replication of these findings in an independent cohort of children. PROCEDURE: . Twenty-three variants were tested for association with...

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PMID: 23441093
DOI: 10.1002/pbc.24505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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