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Article

Transcriptional regulation of TacL-mediated lipoteichoic acids biosynthesis by ComE during competence impacts pneumococcal transformation.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Yao Miao, Wang Kun, Song Guangming, Hu Yumeng, Chen Jiali, Li Tingting, Liang Longying, Wu Jie, Xu Hongmei, Wang Libin, Zheng Yuqiang, Zhang Xuemei, Yin Yibing, Yao Shifei, Wu Kaifeng

Abstract excerpt

Competence development is essential for bacterial transformation since it enables bacteria to take up free DNA from the surrounding environment. The regulation of teichoic acid biosynthesis is tightly controlled during pneumococcal competence; however, the mechanism governing this regulation and its impact on transformation remains poorly understood. We demonstrated that a defect in lipoteichoic acid ligase...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38779562
DOI: 10.3389/fcimb.2024.1375312
PMCID: PMC11109429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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