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Article

Characterization of the role of distinct plasma cell‐free <scp>DNA</scp> species in age‐associated inflammation and frailty

25 Feb 2013

Abstract excerpt

Plasma cell-free DNA (cf-DNA) has recently emerged as a potential biomarker of aging, reflecting systemic inflammation, and cell death. In addition, it has been suggested that cf-DNA could promote autoinflammation. Because the total cf-DNA pool comprises different cf-DNA species, we quantified the plasma levels of gene-coding cf-DNA, Alu repeat cf-DNA, mitochondrial DNA (mtDNA) copy number, and the amounts of...

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PMID: 23438186
DOI: 10.1111/acel.12058

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