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Article

Impact of soluble CD26 on treatment outcome and hepatitis C virus-specific T cells in chronic hepatitis C virus genotype 1 infection.

PloS one - 1 Jan 2013

Söderholm Jonas, Waldenström Jesper, Askarieh Galia, Pilli Massimo, Bochud Pierre-Yves, Negro Francesco, Pawlotsky Jean-Michel, Zeuzem Stefan, Ferrari Carlo, Norkrans Gunnar, Wejstål Rune, Westin Johan, Neumann Avidan U, Haagmans Bart L, Lindh Magnus, Missale Gabriele, Hellstrand Kristoffer, Lagging Martin

Abstract excerpt

BACKGROUND: Interferon and ribavirin therapy for chronic hepatitis C virus (HCV) infection yields sustained virological response (SVR) rates of 50-80%. Several factors such as non-1 genotype, beneficial IL28B genetic variants, low baseline IP-10, and the functionality of HCV-specific T cells predict SVR. With the pending introduction of new therapies for HCV entailing very rapid clearance of plasma HCV RNA, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23437290
DOI: 10.1371/journal.pone.0056991
PMCID: PMC3577643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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