Article
High MIG (CXCL9) plasma levels favours response to peginterferon and ribavirin in HCV-infected patients regardless of DPP4 activity.
Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2016
Johansson Susanne, Talloen Willem, Tuefferd Marianne, Darling Jama, Fanning Gregory, Fried Michael W, Aerssens Jeroen
Abstract excerpt
BACKGROUND & AIMS: Sustained virological response (SVR) following peginterferon (pegIFN) and ribavirin (RBV) treatment in hepatitis C virus (HCV)-infected patients has been linked with the IL28B genotype and lower peripheral levels of the CXCR3-binding chemokine IP-10 (CXCL10). To further improve the understanding of these biomarkers we investigated plasma levels of the other CXCR3-binding chemokines and activity...
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