Article
Inference of cross-level interaction between genes and contextual factors in a matched case-control metabolic syndrome study: a Bayesian approach.
PloS one - 1 Jan 2013
Wang Shi-Heng, Chen Wei J, Chuang Lee-Ming, Hsiao Po-Chang, Liu Pi-Hua, Hsiao Chuhsing K
Abstract excerpt
Genes, environment, and the interaction between them are each known to play an important role in the risk for developing complex diseases such as metabolic syndrome. For environmental factors, most studies focused on the measurements observed at the individual level, and therefore can only consider the gene-environment interaction at the same individual scale. Indeed the group-level (called contextual)...
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