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Article

Identification of genetic loci affecting body mass index through interaction with multiple environmental factors using structured linear mixed model.

Scientific reports - 2 Mar 2021

Jung Hae-Un, Lee Won Jun, Ha Tae-Woong, Kang Ji-One, Kim Jihye, Kim Mi Kyung, Won Sungho, Park Taesung, Lim Ji Eun, Oh Bermseok

Abstract excerpt

Multiple environmental factors could interact with a single genetic factor to affect disease phenotypes. We used Struct-LMM to identify genetic variants that interacted with environmental factors related to body mass index (BMI) using data from the Korea Association Resource. The following factors were investigated: alcohol consumption, education, physical activity metabolic equivalent of task (PAMET), income,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33654129
DOI: 10.1038/s41598-021-83684-1
PMCID: PMC7925554

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