Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration

31 Jan 2013

Abstract excerpt

Aging and oxidative stress seem to be the most important factors in the pathogenesis of age-related macular degeneration (AMD), a condition affecting many elderly people in the developed world. However, aging is associated with the accumulation of oxidative damage in many biomolecules, including DNA. Furthermore, mitochondria may be especially important in this process because the reactive oxygen species produced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23434654
DOI: 10.3390/ijms14022996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular DegenerationPMID 23434654Read ↗

Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD)Semantic proximity Read ↗

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degenerationSemantic proximity Read ↗

Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular DegenerationSemantic proximity Read ↗

DNA damage and repair in age-related macular degenerationSemantic proximity Read ↗

Mitochondrial Dysfunction in Retinal DiseasesSemantic proximity Read ↗

Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.Semantic proximity Read ↗

DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells—Implications for age-related macular degeneration (AMD)Semantic proximity Read ↗

Mitochondrial DNA damage and its potential role in retinal degenerationSemantic proximity Read ↗

Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatmentSemantic proximity Read ↗

Investigating Mitochondria as a Target for Treating Age-Related Macular DegenerationSemantic proximity Read ↗

Oxidation and age-related macular degeneration: insights from molecular biologySemantic proximity Read ↗

Nuclear and Mitochondrial DNA of Age-Related Cataract Patients Are Susceptible to Oxidative DamageSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.