Parthenogenetic stem cells for tissue-engineered heart repair.

doi:10.1172/JCI66854

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Article

Parthenogenetic stem cells for tissue-engineered heart repair.

The Journal of clinical investigation - 1 Mar 2013

Didié Michael, Christalla Peter, Rubart Michael, Muppala Vijayakumar, Döker Stephan, Unsöld Bernhard, El-Armouche Ali, Rau Thomas, Eschenhagen Thomas, Schwoerer Alexander P, Ehmke Heimo, Schumacher Udo, Fuchs Sigrid, Lange Claudia, Becker Alexander, Tao Wen, Scherschel John A, Soonpaa Mark H, Yang Tao, Lin Qiong, Zenke Martin, Han Dong-Wook, Schöler Hans R, Rudolph Cornelia, Steinemann Doris, Schlegelberger Brigitte, Kattman Steve, Witty Alec, Keller Gordon, Field Loren J, Zimmermann Wolfram-Hubertus

Abstract excerpt

Uniparental parthenotes are considered an unwanted byproduct of in vitro fertilization. In utero parthenote development is severely compromised by defective organogenesis and in particular by defective cardiogenesis. Although developmentally compromised, apparently pluripotent stem cells can be derived from parthenogenetic blastocysts. Here we hypothesized that nonembryonic parthenogenetic stem cells (PSCs) can...

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Identifiers

PMID: 23434590
DOI: 10.1172/JCI66854
PMCID: PMC3582145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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