Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation.

Pharmacogenetics and genomics - 1 Oct 2012

Menon Saras, Lea Rod A, Roy Bishakha, Hanna Michelle, Wee Shirley, Haupt Larisa M, Oliver Chris, Griffiths Lyn R

Abstract excerpt

BACKGROUND: Migraine is a chronic disabling neurovascular condition that may in part be caused by endothelial and cerebrovascular disruption induced by hyperhomocysteinaemia. We have previously provided evidence indicating that reduction of homocysteine by vitamin supplementation can reduce the occurrence of migraine in women. The current study examined the genotypic effects of methylenetetrahydrofolate reductase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dietary Supplements
Share to Double-Blind Method

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferredoxin-NADP Reductase

Share to Folic Acid

Share to Migraine with Aura

Share to Vitamin B 12

Share to Vitamin B 6

Share to Vitamins

Source

Identifiers

PMID: 22926161
DOI: 10.1097/FPC.0b013e3283576b6b

Genes

MTHFR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation.PMID 22926161Read ↗

The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.Semantic proximity Read ↗

Targeting MTHFR for the treatment of migrainesSemantic proximity Read ↗

Do folate, vitamins B₆ and B₁₂ play a role in the pathogenesis of migraine? The role of pharmacoepigenomics.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.Semantic proximity Read ↗

Migraine and MTHFR C677T genotype in a population-based sample.Semantic proximity Read ↗

The relationship between homocysteine and genes of folate-related enzymes in migraine patients.Semantic proximity Read ↗

Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.Semantic proximity Read ↗

Effects of dietary folate intake on migraine disability and frequency.Semantic proximity Read ↗

The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.Semantic proximity Read ↗

Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.Semantic proximity Read ↗

Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.