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Article

Endothelial outgrowth cells shift macrophage phenotype and improve kidney viability in swine renal artery stenosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2013

Eirin Alfonso, Zhu Xiang-Yang, Li Zilun, Ebrahimi Behzad, Zhang Xin, Tang Hui, Korsmo Michael J, Chade Alejandro R, Grande Joseph P, Ward Christopher J, Simari Robert D, Lerman Amir, Textor Stephen C, Lerman Lilach O

Abstract excerpt

OBJECTIVE: Endothelial outgrowth cells (EOC) decrease inflammation and improve endothelial repair. Inflammation aggravates kidney injury in renal artery stenosis (RAS), and may account for its persistence upon revascularization. We hypothesized that EOC would decrease inflammatory (M1) macrophages and improve renal recovery in RAS. APPROACH AND RESULTS: Pigs with 10 weeks of RAS were studied 4 weeks after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23430615
DOI: 10.1161/ATVBAHA.113.301164
PMCID: PMC3644980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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