Article
Exon 2 DNA sequence of the HLA-DRw13b allele obtained from genomes of five different individuals.
Molecular immunology - 1 Mar 1990
Corell A, Martin-Villa J M, Varela P, Vicario J L, Martinez-Laso J, Arnaiz-Villena A
Abstract excerpt
Exon 2 nucleotide sequence of the DRB1 gene encoding the HLA-DRw13b allele defined by DNA-RFLP (Restriction Fragment Length Polymorphism) typing, has been obtained by using five heterozygous individuals genomic DNA and a non isotopic automated "dideoxi" methodology. Its comparison with other known homologous DRB1 sequences suggests that two different mechanisms which generate HLA allele variability may have...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA
- Exons
- Genome, Human
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- Humans
- Molecular Sequence Data
