Article
Identification of a novel HLA DRB1 exon 2 sequence, DRB1*1345.
Tissue antigens - 1 Feb 2002
Bengtsson Mats, Jansson I E, Danielsson F, Henrysson H, Källsten K
Abstract excerpt
Five different haplotypes in the human HLA D region are recognized based on their gene composition. The HLA DR52 associated DRB1 alleles include DRB1*03/08/11/12/13/14 and are characterized by the YST sequence motif in the codons 10-12 but vary in other polymorphic regions. The mechanisms generating the extensive variability are not entirely clear. Some alleles have probably arisen from point mutations, but most...
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