Article
New HLA-DRB1* nucleotide sequence of Italian origin: HLA-DRB1*13022.
Tissue antigens - 1 Aug 2000
Martinetti M, Pizzochero C, Asti M, Salvaneschi L
Abstract excerpt
High-resolution polymerase chain reaction using sequence-specific primer typing of the HLA-DRB1 gene of an Italian patient waiting for unrelated bone marrow transplantation revealed a new allelic variant of HLA-DRB1*13. Sequencing the exon 2 of DRB1* gene demonstrated a G-->C transition at the nucleotide 216 resulting in a silent mutation at codon 72: CGG-->CGC. The closest sequence was the HLA-DRB1*1302 and the...
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