Article
Epigenomic model of cardiac enhancers with application to genome wide association studies.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2013
Sahu Avinash Das, Aniba Radhouane, Chang Yen-Pei Christy, Hannenhalli Sridhar
Abstract excerpt
Mammalian gene regulation is often mediated by distal enhancer elements, in particular, for tissue specific and developmental genes. Computational identification of enhancers is difficult because they do not exhibit clear location preference relative to their target gene and also because they lack clearly distinguishing genomic features. This represents a major challenge in deciphering transcriptional regulation....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
