Article
The albino mutation of tyrosinase alters ocular angiogenic responsiveness.
Angiogenesis - 1 Jul 2013
Rogers Michael S, Adini Irit, McBride Aaron F, Birsner Amy E, D'Amato Robert J
Abstract excerpt
We have observed substantial differences in angiogenic responsiveness in mice and have mapped the genetic loci responsible for these differences. We have found that the albino mutation is one of the loci responsible for such differences. Using B6.A consomic strains, we determined that chromosome 7 bears a locus that inhibits VEGF-induced corneal neovascularization. F2 crosses between B6.A<Chromosome 7> consomic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.