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Article

Tyrosinase is the modifier of retinoschisis in mice.

Genetics - 1 Dec 2010

Johnson Britt A, Cole Brian S, Geisert Eldon E, Ikeda Sakae, Ikeda Akihiro

Abstract excerpt

X-linked retinoschisis (XLRS) is a form of macular degeneration with a juvenile onset. This disease is caused by mutations in the retinoschisin (RS1) gene. The major clinical pathologies of this disease include splitting of the retina (schisis) and a loss in synaptic transmission. Human XLRS pati...

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Identifiers

PMID: 20876567
DOI: 10.1534/genetics.110.120840
PMCID: PMC2998315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20876567-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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