Article
Genetic analysis of a population heavy drinking phenotype identifies risk variants in whites.
Journal of clinical psychopharmacology - 1 Apr 2013
Hamidovic Ajna, Goodloe Robert J, Young Taylor R, Styn Mindi A, Mukamal Kenneth J, Choquet Helene, Kasberger Jay L, Buxbaum Sarah G, Papanicolaou George J, White Wendy, Volcik Kelly, Spring Bonnie, Hitsman Brian, Levy Daniel, Jorgenson Eric
Abstract excerpt
Genetic association studies thus far have used detailed diagnoses of alcoholism to identify loci associated with risk. This proof-of-concept analysis examined whether population data of lifetime heaviest alcohol consumption may be used to identify genetic loci that modulate risk. We conducted a genetic association study in European Americans between variants in approximately 2100 genes and alcohol consumption as...
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