Article
Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids.
Atherosclerosis - 1 Apr 2011
Walker C G, Loos R J F, Olson A D, Frost G S, Griffin B A, Lovegrove J A, Sanders T A B, Jebb S A
Abstract excerpt
OBJECTIVE: SNPs identified from genome-wide association studies associate with lipid risk markers of cardiovascular disease. This study investigated whether these SNPs altered the plasma lipid response to diet in the 'RISCK' study cohort. METHODS: Participants (n=490) from a dietary intervention to lower saturated fat by replacement with carbohydrate or monounsaturated fat, were genotyped for 39 lipid-associated...
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