Article
Metabolic model refinement using phenotypic microarray data.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Gawand Pratish, Yang Laurence, Cluett William R, Mahadevan Radhakrishnan
Abstract excerpt
Phenotypic microarray (PM) is a standardized, high-throughput technology for profiling phenotypes of microorganisms, which allows for characterization on around 2,000 different media conditions. The data generated using PM can be incorporated into genome-scale metabolic models to improve their predictive capability. In addition, a comparison of phenotypic profiles of wild-type and gene knockout mutants can give...
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