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Sex Determination in the Mammalian Germline

30 Aug 2017

Abstract excerpt

Sexual reproduction crucially depends on the production of sperm in males and oocytes in females. Both types of gamete arise from the same precursor, the germ cells. We review the events that characterize the development of germ cells during fetal life as they commit to, and prepare for, oogenesis or spermatogenesis. In females, fetal germ cells enter meiosis, whereas in males they delay meiosis and instead lose...

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PMID: 28853925
DOI: 10.1146/annurev-genet-120215-035449

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