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Article

<i>Shigella</i> impairs T lymphocyte dynamics in vivo

24 Jan 2013

Abstract excerpt

The Gram-negative enteroinvasive bacterium Shigella flexneri is responsible for the endemic form of bacillary dysentery, an acute rectocolitis in humans. S. flexneri uses a type III secretion system to inject effector proteins into host cells, thus diverting cellular functions to its own benefit. Protective immunity to reinfection requires several rounds of infection to be elicited and is short-lasting,...

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PMID: 23417297
DOI: 10.1073/pnas.1300981110

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