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Article

Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer.

Oncogene - 13 Feb 2014

Tang J, Li Y, Lyon K, Camps J, Dalton S, Ried T, Zhao S

Abstract excerpt

Herein we report a proof-of-principle study illustrating a novel dog-human comparison strategy that addresses a central aim of cancer research, namely cancer driver-passenger distinction. We previously demonstrated that sporadic canine colorectal cancers (CRCs) share similar molecular pathogenesis mechanisms as their human counterparts. In this study, we compared the genome-wide copy number abnormalities between...

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Identifiers

PMID: 23416983
DOI: 10.1038/onc.2013.17
PMCID: PMC3932186

Genes

AVL9
RASA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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