Article
Comparative molecular life history of spontaneous canine and human gliomas
2019-06-17
Abstract excerpt
<h4>Summary</h4> Sporadic gliomas in companion dogs provide a window on the interaction between tumorigenic mechanisms and host environment. We compared the molecular profiles of canine gliomas with those of human pediatric and adult gliomas to characterize evolutionarily conserved mammalian mutational processes in gliomagenesis. Employing whole genome-, exome-, transcriptome-and methylation-sequencing of 81 cani...
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Identifiers and source
- Literature Corpus work
- 81d4245f-4fd6-52b8-b9b5-e1422bb02001
- DOI
- 10.1101/673822