Article
RAET1/ULBP alleles and haplotypes among Kolla South American Indians.
Human immunology - 1 Jun 2013
Cox Steven T, Arrieta-Bolaños Esteban, Pesoa Susanna, Vullo Carlos, Madrigal J Alejandro, Saudemont Aurore
Abstract excerpt
NK cell cytolysis of infected or transformed cells can be mediated by engagement of the activating immunoreceptor NKG2D with one of eight known ligands (MICA, MICB and RAET1E-N) and is essential for innate immunity. As well as diversity of NKG2D ligands having the same function, allelic polymorphism and ethnic diversity has been reported. We previously determined HLA class I allele and haplotype frequencies in...
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