Article
Coffee prevents early events in tamoxifen-treated breast cancer patients and modulates hormone receptor status.
Cancer causes & control : CCC - 1 May 2013
Simonsson Maria, Söderlind Viktoria, Henningson Maria, Hjertberg Maria, Rose Carsten, Ingvar Christian, Jernström Helena
Abstract excerpt
PURPOSE: Whether coffee modulates response to endocrine therapy in breast cancer patients is currently unknown. The CYP1A2 and CYP2C8 enzymes contribute to tamoxifen and caffeine metabolism. The purpose was to investigate the impact of coffee consumption on tumor characteristics and risk for early events in relation to breast cancer treatment and CYP1A2 and CYP2C8 genotypes. METHODS: Questionnaires regarding...
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