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Article

[Detection of S315T mutation in the katg gene as a strategy for identification of isoniazid-resistant Mycobacterium tuberculosis in a reference laboratory].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia - 1 Dec 2012

Romay Zolay, Arráiz Nailet, Fuenmayor Alisbet, Ramírez Carmen, Rojas Luis, París Rafael

Abstract excerpt

INTRODUCTION: The emergence of strains of Mycobacterium tuberculosis resistant to drugs is a public health problem. AIM: To characterize the resistance to isoniazid (INH) in M. tuberculosis. METHODS: Phenotypic and genotypic methods were used to determine the contribution of mutations at 315 codon of katG gene to the phenotypic expression of resistance. The analysis of susceptibility to antibiotics was performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23412028
DOI: 10.4067/S0716-10182012000700004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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