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Article

Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression.

Genetics - 1 Apr 2013

Shively Christian A, Eckwahl Matthew J, Dobry Craig J, Mellacheruvu Dattatreya, Nesvizhskii Alexey, Kumar Anuj

Abstract excerpt

The budding yeast Saccharomyces cerevisiae can respond to nutritional and environmental stress by implementing a morphogenetic program wherein cells elongate and interconnect, forming pseudohyphal filaments. This growth transition has been studied extensively as a model signaling system with similarity to processes of hyphal development that are linked with virulence in related fungal pathogens. Classic studies...

Topics

Cyclin B
Epistasis, Genetic
Gene Deletion
Gene Regulatory Networks
Genome, Fungal
Hyphae
MAP Kinase Signaling System
Mitogen-Activated Protein Kinases
Phenotype
S Phase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23410832
DOI: 10.1534/genetics.112.147876
PMCID: PMC3606104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23410832-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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