Article
Angiogenin in Parkinson disease models: role of Akt phosphorylation and evaluation of AAV-mediated angiogenin expression in MPTP treated mice.
PloS one - 1 Jan 2013
Steidinger Trent U, Slone Sunny R, Ding Huiping, Standaert David G, Yacoubian Talene A
Abstract excerpt
The angiogenic factor, angiogenin, has been recently linked to both Amyotrophic Lateral Sclerosis (ALS) and Parkinson Disease (PD). We have recently shown that endogenous angiogenin levels are dramatically reduced in an alpha-synuclein mouse model of PD and that exogenous angiogenin protects agai...
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