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Polymorphisms of nucleotide excision repair genes predict melanoma survival.

The Journal of investigative dermatology - 1 Jul 2013

Li Chunying, Yin Ming, Wang Li-E, Amos Christopher I, Zhu Dakai, Lee Jeffrey E, Gershenwald Jeffrey E, Grimm Elizabeth A, Wei Qingyi

Abstract excerpt

Melanoma is the most highly malignant skin cancer, and nucleotide excision repair (NER) is involved in melanoma susceptibility. In this analysis of 1,042 melanoma patients, we evaluated whether genetic variants of NER genes may predict survival outcome of melanoma patients. We used genotyping data of 74 tagging single-nucleotide polymorphisms (tagSNPs) in eight core NER genes from our genome-wide association...

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Endonucleases
Kaplan-Meier Estimate
Melanoma
Proportional Hazards Models
Skin Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Xeroderma Pigmentosum

Xeroderma Pigmentosum Group D Protein

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Identifiers

PMID: 23407396
DOI: 10.1038/jid.2012.498
PMCID: PMC3660504

Genes

ERCC2
ERCC5
XPC
ERCC1
ERCC3
ERCC4
XPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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