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Article

ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln polymorphisms are independent prognostic factors for the clinical course of melanoma.

The Journal of investigative dermatology - 1 Jun 2011

Schrama David, Scherer Dominique, Schneider Michael, Zapatka Marc, Bröcker Eva-Bettina, Schadendorf Dirk, Ugurel Selma, Kumar Rajiv, Becker Jürgen C

Abstract excerpt

Genetic variants in DNA repair enzymes contribute to the susceptibility to cutaneous melanoma; consequently, we analyzed whether common nonsynonymous single-nucleotide polymorphisms in DNA repair enzyme genes might also influence the course of disease. To this end, we determined eight polymorphisms of seven different DNA repair enzymes in 742 patients with cutaneous melanoma, and correlated these with overall...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21390047
DOI: 10.1038/jid.2011.35

Genes

ERCC5
ERCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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