Article
Do not underestimate nucleotide excision repair: it predicts not only melanoma risk but also survival outcome.
The Journal of investigative dermatology - 1 Jul 2013
Emmert Steffen, Kraemer Kenneth H
Abstract excerpt
Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions, thereby maintaining genomic integrity. Dr Qingyi Wei's group demonstrated over the last decade that NER fidelity and single-nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In this issue, Li et al. provide evidence that SNPs in NER genes may also predict melanoma survival.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.