Article
CACNA1C polymorphisms Impact Cognitive Recovery in Patients with Bipolar Disorder in a Six-week Open-label Trial.
Scientific reports - 1 Aug 2017
Lin Kangguang, Xu Guiyun, Shi Lingling, Lu Weicong, Guan Lijie, Ouyang Huiyi, Chen Kun, Dang Yamei, Zhou Libing, So Kwok-Fai
Abstract excerpt
Cognitive impairments in bipolar patients deteriorate as the disorder progresses. Little is known about whether genetic risks impact cognitive recovery during the course from depression to remission. In this six-week open-label trial, we shed light on the impacts of six single nucleotide polymorphisms (SNPs) in the calcium voltage-gated channel subunit alpha1 C (CACNA1C) gene on cognitive recovery in 192 bipolar...
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