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Article

Gene expression profile of highly purified bone marrow mast cells in systemic mastocytosis.

The Journal of allergy and clinical immunology - 1 Apr 2013

Teodosio Cristina, García-Montero Andrés C, Jara-Acevedo María, Sánchez-Muñoz Laura, Pedreira Carlos E, Álvarez-Twose Ivan, Matarraz Sergio, Morgado José M, Bárcena Paloma, Matito Almudena, Mayado Andrea, Sanchez Maria Luz, Diez-Campelo María, Escribano Luis, Orfao Alberto

Abstract excerpt

BACKGROUND: Despite the fact that a great majority (>90%) of patients with systemic mastocytosis (SM) carry a common genetic lesion, the D816V KIT mutation, little is known regarding the molecular and biological pathways underlying the clinical heterogeneity of the disease. OBJECTIVE: We sought to analyze the gene expression profile (GEP) of bone marrow mast cells (BMMCs) in patients with SM and its association...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23403045
DOI: 10.1016/j.jaci.2012.12.674

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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