Article
Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes.
The Journal of allergy and clinical immunology - 1 Mar 2010
Teodosio Cristina, García-Montero Andrés C, Jara-Acevedo María, Sánchez-Muñoz Laura, Alvarez-Twose Ivan, Núñez Rosa, Schwartz Lawrence B, Walls Andrew F, Escribano Luis, Orfao Alberto
Abstract excerpt
BACKGROUND: Systemic mastocytosis (SM) is a heterogeneous group of disorders with distinct clinical and biological behavior. Despite this, little is known about the immunophenotypic features of the distinct diagnostic categories of SM. OBJECTIVE: To analyze the immunophenotypic characteristics of bone marrow (BM) mast cells (MCs) of different subtypes of SM. METHODS: Bone marrow samples from 123 patients with...
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