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Article

HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity

9 Feb 2013

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HDAC6 is a transcriptional regulator of the histone deacetylase family, subfamily 2. Previous studies have shown that HDAC6 plays critical roles in transcription regulation, cell cycle progression and developmental events. However, its biological roles in the development of HCC remain largely unexplored. In the present study, we found that...

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PMID: 23402884
DOI: 10.1016/j.febslet.2013.02.001

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