Article
X and Y chromosome complement influence adiposity and metabolism in mice.
Endocrinology - 1 Mar 2013
Chen Xuqi, McClusky Rebecca, Itoh Yuichiro, Reue Karen, Arnold Arthur P
Abstract excerpt
Three different models of MF1 strain mice were studied to measure the effects of gonadal secretions and sex chromosome type and number on body weight and composition, and on related metabolic variables such as glucose homeostasis, feeding, and activity. The 3 genetic models varied sex chromosome complement in different ways, as follows: 1) "four core genotypes" mice, comprising XX and XY gonadal males, and XX and...
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