Article
Phosphorylation of frizzled-3.
The Journal of biological chemistry - 28 Apr 2006
Yanfeng Wang A, Tan Change, Fagan Robert J, Klein Peter S
Abstract excerpt
Wnts are secreted proteins important to many biological processes. frizzled genes encode a family of Wnt receptors that signal to the intracellular compartment through the cytosolic protein Disheveled. Limited information is available concerning the regulation of Frizzleds at a biochemical level. We report here that Xenopus Frizzled-3 is phosphorylated in a Disheveled-dependent manner that appears to require the...
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