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Article

Dvl3 translocates IPMK to the cell membrane in response to Wnt.

Cellular signalling - 1 Dec 2012

Wang Ying, Wang Hsien-yu

Abstract excerpt

Wnt3a binds Frizzled-1 and the LRP5/6 co-receptors, ultimately activating Lef/Tcf-sensitive gene transcription in development. Inositol polyphosphate multikinase, IPMK, which possesses inositol phosphate kinase and lipid inositol kinase activities, is essential in Wnt3a regulation of its canonical pathway as well as physiologically in AMPK signaling. In the current report we show that translocation of IPMK to the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 22940627
DOI: 10.1016/j.cellsig.2012.08.009
PMCID: PMC3482508

Genes

IPMK
LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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