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Article

Cyclin D1 polymorphism in non-small cell lung cancer in a Portuguese population.

Cancer biomarkers : section A of Disease markers - 1 Jan 2012

Catarino R, Coelho A, Nogueira A, Araújo A, Gomes M, Lopes C, Medeiros R

Abstract excerpt

Cyclin D1 (CCND1) is a key regulatory protein of the cell cycle. The purpose of our study was to assess the role of CCND1 genetic variants influencing the genetic susceptibility of non-small cell lung cancer (NSCLC). We conducted a study of 1234 individuals, including 892 controls and 342 cases. Individuals carrying two G-alleles have a 2-fold increased risk for the development of NSCLC and the waiting time for...

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Source

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Identifiers

PMID: 23396251
DOI: 10.3233/CBM-130294
PMCID: PMC13016372

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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