Article
Effects of cyclin D1 (CCND1) polymorphism on susceptibility to lung cancer in a North Indian population.
Cancer genetics and cytogenetics - 15 Oct 2006
Sobti R C, Kaur Pushpinder, Kaur Satinder, Singh Jagmohan, Janmeja A K, Jindal S K, Kishan J, Raimondi Sara
Abstract excerpt
Cyclin D1 is involved in normal regulation of the cell cycle and plays an important role in the transition from G1 to S phase of the cell cycle. The CCND1 gene has a G-->A polymorphism in exon 4 that increases the frequency of alternate splicing. We analyzed the potential role of CCND1 gene polymorphisms in lung cancer patients (n = 151) and in a matched control population (n = 151). DNA was isolated from blood...
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