Article
Cyclin D1 gene polymorphism and susceptibility to lung cancer in a Chinese population.
Carcinogenesis - 1 Sept 2003
Qiuling Shi, Yuxin Zheng, Suhua Zheng, Cheng Xiao, Shuguang Leng, Fengsheng He
Abstract excerpt
The objective was to study the relationship between cyclin D1 gene (CCND1) polymorphism and lung cancer in the Chinese population. Blood samples of 182 cases and 185 controls were collected from a hospital based case-control study. PCR-SSCP was used to examine the G/A polymorphism in exon 4 of CCND1. The results showed that the frequencies of the CCND1 AA, GA and GG genotypes were 31.3, 46.7 and 22.0%...
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