Sodium fluoride lacks mitogenic activity for fetal human bone cells in vitro.

doi:10.1002/jbmr.5650051321

Article

Sodium fluoride lacks mitogenic activity for fetal human bone cells in vitro.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 1990

Kopp J B, Robey P G

Abstract excerpt

Sodium fluoride has been shown to be effective therapy for some patients with vertebral osteoporosis. Data from histomorphometric studies in patients and animals suggest that at least part of this effect may be a consequence of a proliferative effect of fluoride, either direct or indirect, on the...

Topics

Bone and Bones
Cell Division
Cells, Cultured
Humans
Mitogens
Osteoblasts
Phenotype
Sodium Fluoride
Thymidine

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