Article
Absence of glutamine supplementation prevents differentiation of murine calvarial osteoblasts to a mineralizing phenotype.
Calcified tissue international - 1 Dec 2011
Brown Philip M, Hutchison James D, Crockett Julie C
Abstract excerpt
Osteoblasts in vitro differentiate from a proliferating to a mineralizing phenotype upon transfer to a medium rich in beta-glycerophosphate and ascorbic acid. The nutritional requirements of the cells at different stages of this differentiation process are not known. In other cell types, nutritional supplementation during surgery can improve the outcome in terms of speed of patient recovery and prognosis. There...
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