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Article

Structural characterization of the complete human perlecan gene and its promoter.

1 Nov 1993

Abstract excerpt

The complete intron-exon organization of the gene encoding human perlecan (HSPG2), the major heparan sulfate proteoglycan of basement membranes, has been elucidated, and specific exons have been assigned to coding sequences for the modular domains of the protein core. The gene was composed of 94 exons, spanning > 120 kbp of genomic DNA. The exon arrangement was analyzed vis-à-vis the modular structure of the...

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Identifiers

PMID: 8234307
DOI: 10.1073/pnas.90.21.10404

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