Article
Host-derived nitrate boosts growth of E. coli in the inflamed gut.
Science (New York, N.Y.) - 8 Feb 2013
Winter Sebastian E, Winter Maria G, Xavier Mariana N, Thiennimitr Parameth, Poon Victor, Keestra A Marijke, Laughlin Richard C, Gomez Gabriel, Wu Jing, Lawhon Sara D, Popova Ina E, Parikh Sanjai J, Adams L Garry, Tsolis Renée M, Stewart Valley J, Bäumler Andreas J
Abstract excerpt
Changes in the microbial community structure are observed in individuals with intestinal inflammatory disorders. These changes are often characterized by a depletion of obligate anaerobic bacteria, whereas the relative abundance of facultative anaerobic Enterobacteriaceae increases. The mechanisms by which the host response shapes the microbial community structure, however, remain unknown. We show that nitrate...
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