Revisiting nitrogen assimilation strategies in the mammalian gut: lessons from Enterobacteriaceae as pathobiont models and a challenge to the limitation paradigm

Abstract excerpt

The intestinal microbiome is dependent on nitrogen to support growth, yet the extent of nitrogen-limitation for microbial expansion in the mammalian gut remains debated. Classical perspectives describe the colon as nitrogen-limited due to the early absorption of dietary nitrogen in the small intestine, prompting the evolution of nitrogen-scavenging. In this mini-review, we focus on Enterobacteriaceae, facultative...

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