Article
Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism.
Toxicology and applied pharmacology - 15 Dec 2015
Dheer Rishu, Patterson Jena, Dudash Mark, Stachler Elyse N, Bibby Kyle J, Stolz Donna B, Shiva Sruti, Wang Zeneng, Hazen Stanley L, Barchowsky Aaron, Stolz John F
Abstract excerpt
Chronic exposure to arsenic in drinking water causes cancer and non-cancer diseases. However, mechanisms for chronic arsenic-induced pathogenesis, especially in response to lower exposure levels, are unclear. In addition, the importance of health impacts from xeniobiotic-promoted microbiome changes is just being realized and effects of arsenic on the microbiome with relation to disease promotion are unknown. To...
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